The incident comes a day after a Palestinian killed seven people near a synagogue following Israel’s deadly raid in the Jenin refugee camp.
Two people have been injured in a shooting outside the Old City in the Silwan neighbourhood, just outside occupied East Jerusalem’s old, walled city, Israel’s rescue emergency response service (MDA) and Israeli Army Radio said.
An MDA spokesperson said two gunshot victims, a father, 47, and son, 23, were in serious condition with “gunshot wounds to their upper body”.
A police spokesman told Army Radio that Saturday’s incident was a “terrorist attack” and that the assailant, who was “neutralised and injured”, is a 13-year-old Palestinian boy from occupied East Jerusalem.
The incident comes a day after a Palestinian attacker killed seven people near a synagogue on the outskirts of the city.
On Thursday, Israel carried out a deadly raid in the Jenin refugee camp in the occupied West Bank. Ten Palestinians were killed, including an elderly woman, after dozens of Israeli soldiers attacked a house the army said housed suspected fighters, leading to several hours of intense confrontations.
It was one of the deadliest Israeli army raids in the occupied West Bank since the second intifada, or Palestinian uprising, of 2000 to 2005.
A 22-year-old Palestinian man was also shot by Israeli forces in the town of al-Ram, north of Jerusalem, on Thursday.
Israel also launched multiple air attacks on the blockaded Gaza Strip overnight on Thursday.
Local sources in Gaza told Al Jazeera that Israeli warplanes had hit al-Maghazi refugee camp in the centre of the territory, with at least 13 strikes by the early hours of Friday.
Police said they arrested 42 Palestinians following Friday’s attack.
In a separate statement, police said the force had been placed on the “highest level” of alert following the attack.
Before Friday’s shooting, at least 30 Palestinians were killed this year and the Palestinian Authority, which has limited governing powers in the occupied West Bank, said it was suspending a security cooperation arrangement with Israel.